Reg. No.  G2470 Act 36/1947
Namibia Reg No. NSR-0727

AVAILABLE THROUGH VETS ONLY

Engemycin®  10 % is an aqueous oxytetracycline injectable solution for the treatment and control of disease conditions caused by or associated with oxytetracycline susceptible organisms.

Indications
Cattle : For the treatment of tick-borne gallsickness (anaplasmosis), heartwater, bacterial pneumonia,  mastitis, bacterial enteritis, navel/joint-ill and bacterial wound infections.

Horses :  For the treatment of strangles, bacterial pneumonia and enteritis.

Pigs : For the treatment of bacterial pneumonia,  mastitis, bacterial enteritis, navel/joint-ill and bacterial wound infections.

Sheep and Goats : For the treatment of heartwater, bacterial pneumonia, footrot, mastitis, navel/joint-ill and bacterial wound infections.

Storage
Store in the dark below 25 °C.
Do not freeze.
Protect from exposure to direct sunlight.

Composition
Engemycin® 10 % is an aqueous solution containing oxytetracycline in a complex with magnesium and polyvinylpyrolidone.

Content
Each 1 mℓ of Engemycin®  10 %  contains 100 mg oxytetracyline in a complex with magnesium oxide and polyvinylpyrolidone in water for injection.  It contains sodium formaldehydesulfoxylate as a preservative.

Warnings
Withdrawal periods : Meat and other organs: 14 days after the last dosage.
Milk: 60 hours after the last dosage.
The use of tetracyclines during the period of tooth development including late pregnancy may lead to tooth discolouration.
A darkened solution must be discarded.
Rapid intravenous injection may result in an acute side reaction and collapse.
Keep out of reach of children and uninformed persons.
Although this remedy has been tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons.  If this is suspected, seek veterinary advice and notify the registration holder.

Precautions
Do not administer to animals known to be allergic to oxytetracyclines. (Infrequent allergies may occur).
Do not inject piglets with iron preparations on the same day.
Do not dilute with calcium salts as this may lead to precipitation of crystals which would make the solution not suitable for intravenous infusion.
Oxytetracycline must be used with caution in animals with existing kidney impairment.
Consult a veterinarian for an accurate diagnosis.

Directions for use
Use only as directed.
Three to five dosages are required to control bacterial infections.
Repeat intramuscular or subcutaneous injections should be given at different sites.  Not more than 20 mℓ should be given at any one site.
Intravenous injections should be given slowly over a period of at least one minute.
For the indication of Anaplasmosis/Heartwater, the recommended dose is 10 mg/Kg i.v./i.m.
Observe aseptic conditions when administering the injection.

Cattle and Horses : 
1 mℓ  per 10 kg  body mass i.v./i.m. (10 mg/Kg).   Intramuscular
injections should be made deep into the fleshy part of the muscle.  Administer in a minimum of 2 locations to limit the volume per site.

Pigs :
Dosage:  10  mg/kg (1 mℓ/10 kg body mass) s.c. or i.m.
In very young pigs under 10 kg body mass, the subcutaneous route is preferred.
Pigs in excess of 10 kg body mass, administer by intramuscular injection at one site in the neck.
In pigs weighing over 100 kg the dose should be divided and administered at 2 injection sites.
Do not administer more than 0,5 mℓ oxytetracycline in piglets of less than 2 kg body mass.

Sheep and Goats : 
Dosage:  10 mg/kg body mass i.v./i.m. (1 mℓ /10 kg body mass)
In sheep and goats over 50 kg body mass the dose should be divided and administered at 2 injection sites.

Presentation
100 mℓ and 500 mℓ amber bottles or PET flasks each packed in a cardboard box.

REGISTRATION HOLDER:
Intervet S.A. (Pty) Ltd
Co. Reg. No. 1991/006580/07