For the prevention of neonatal Escherichia coli enterotoxicosis in piglets. Progeny of properly vaccinated sows and gilts derive a passive immunity via the colostrum.

Storage Instructions:

• Store in the dark between 2ºC and 8ºC. Do not freeze.
• Allow the vaccine to gradually reach room temperature (20ºC to 25ºC) prior to use.
• Avoid prolonged and repetitive exposure to high ambient temperatures.
• Protect from direct sunlight.

Composition: Porcilis® Coli contains LT toxoid and the antigens F4 ab (K88 ab), F4 ac (K88 ac), F5 (K99) and F6 (987P) of Escherichia coli. The active components are suspended in the aqueous phase of a water-in-oil emulsion.

Contents:

Each 2 ml dose of Porcilis® Coli vaccine contains at least 100 ED50 of each of the following active components: The E.coli LT toxoid and the E.coli fimbrial antigens F4 ab (K88 ab), F4 ac (K88 ac), F5 (K99) and F6 (987P). These active components are suspended in the aqueous phase of a water-in-oil emulsion.

Warnings:

• Shake the bottle well prior to and regularly during administration.
• Opened vials should be used within 3 hours.
• Do not mix with other vaccines or substances.  
• Destroy any unused vaccine by, for example, burning and dispose of all vaccine containers after vaccination.
• Do not store partially used containers for future use, and use the entire contents when opened.
• Accidental self injection may lead to a severe allergic reaction. Consult a physician immediately informing him/her that the vaccine contains a mineral oil.
• Keep out of reach of children, uninformed persons and animals.
• Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Precautions:

• Only healthy animals should be vaccinated.
• Observe aseptic precautions. Ensure that the vaccination equipment (needles, syringes, etc.) are clean and sterile prior to use.
• Ensure that all equipment is kept clean and sterile during vaccination.
• Avoid intravenous injection.
• It is good vaccination practice when handling the vaccine, to avoid contact with the eyes, hands and clothing.

Directions for Use:

Use only as directed.

Vaccination Programme:

• Sows and Gilts which have not been vaccinated with this product, should be given a primary, followed by a secondary vaccination. Interval between these vaccinations should be 6 weeks.
• Re-vaccinations should be carried out between every two farrowings. Generally speaking this means every 5 to 6 months.
• To enhance colostral protection of the piglets, sows and gilts should be vaccinated 3 to 4 weeks before farrowing. 
• All of the breeding stock present on a farm may be vaccinated at one time.
• Un-vaccinated animals newly introduced to the herd should be vaccinated twice, with an interval of 6 weeks.

Dosage and Administration:

Sows and Gilts: 2 ml.  The vaccine should be administered intramuscularly by injection in the neck or in the area behind the ear.

Vaccination Reactions:

• In animals vaccinated for the first time some mild transient clinical reactions may occur (slight fever, some decreased liveliness, for a maximum of 24 hours). For some weeks after vaccination a slight swelling may be felt at the site of vaccination. Local tissue reactions may occur.
• The risk of abortion in sows is so small as to be negligible and is in any case no greater than with any other vaccination.
• If sows are vaccinated within two weeks from farrowing the risks are the same as with any other injection in this period.

Presentation:

20 ml(10 doses) and 50 ml (25 doses) glass vials each packed in a cardboard box.