For use by or under the control of a Veterinarian only.
Reg. No. G2323 Act 36/1947

For active immunisation of young puppies against canine distemper and canine parvovirus disease.

Storage Instructions:

• Store in the dark between 2 °C and 8 °C. Do not freeze.
• Avoid prolonged or repetitive exposure to high ambient temperatures.
• Allow the vaccine to gradually reach room temperature (20 °C to 25 °C) prior to use.
• Protect from direct sunlight.
• The solvent may be stored at room temperature.

Composition:
It is a combination of live attenuated strains of canine distemper virus and canine parvovirus grown in cell-line tissue culture and presented as a freeze-dried plug. Each vial contains a single dose for reconstitution.

Contents:
Each vial contains canine distemper virus, strain Onderstepoort ³ 10⁵ TCID₅₀ and canine parvovirus, strain 154 ³ 10⁷ TCID ₅₀.

Warnings:

• Destroy any unused vaccine by, for example, burning and dispose of all vaccine containers after vaccination.
• Do not store partially used containers for future use, and use the entire contents when opened.
• Accidental self injection may lead to a severe allergic reaction. Consult a physician.
• Keep out of reach of children and uninformed persons.
• Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Precautions:

• Only healthy puppies should be vaccinated and an adequate clinical examination should be made prior to inoculation.
• Observe aseptic precautions. Ensure that the vaccination equipment (needles, syringes, etc.) are clean and sterile prior to use.
• Avoid contamination of the vaccine with traces of disinfectant or spirit.
• It is good vaccination practice when handling the vaccine to avoid contact with the eyes, hands and clothing.
• Hypersensitivity reactions, following administration are rare but as with all vaccines it may occasionally be encountered. In this event administration of adrenaline injection by the subcutaneous route may be indicated.
• Avoid contamination of the vaccine with traces of disinfectant and spirit.
• Avoid intravenous injection.
• Directions for Use: Use only as directed.
• Puppies should be vaccinated with a single dose of Nobivac Puppy DP at 6 to 7 weeks of age preferably before weaning.
• Puppies which have received Nobivac Puppy DP should be further immunised with a standard vaccination course starting at 9 to 12 weeks of age.

Vaccination Programme:

Novivac Puppy DP will immunise puppies successfully against parvovirus and distemper. Puppies should be vaccinated with a single dose of Nobivac Puppy DP at 6 to 7 weeks of age, preferably before weaning. Puppies which have received Nobivac Puppy DP should be further immunised with a standard recommended vaccination course starting at 9 to 12 weeks of age. This course should include further vaccinations against canine distemper and canine parvovirus disease, and vaccinations against canine hepatitis, leptospirosis and rabies.

The use of the Nobivac range of canine vaccines is recommended for this purpose and the following programme is recommended for puppies that have received Nobivac Puppy DP at 6 weeks of age:

• 9 weeks: 1 dose of Nobivac L (if there is a high risk of early exposure to canine distemper virus or canine parvovirus than a dose of Nobivac Parvo-C, Nobivac DH or Nobivac DHP can be given as well).
• 12 weeks: 1 dose of Nobivac DHP reconstituted with one vial of Nobivac RL or Nobivac L. If this course is not started until, or after, 12 weeks of age then Nobivac DHP and Nobivac RL/L should be given first, followed by an additional dose of Nobivac L 2 to 4 weeks later.

Dosage and Administration:
The contents of one vial of reconstituted vaccine should be injected subcutaneously.

Reconstitute immediately prior to use by the addition of the contents of one vial (1,0 ml) of Nobivac Solvent. The vaccine should be reconstituted using Nobivac Solvent immediately prior to use. The vaccine should be administered by subcutaneous injection in the neck or chest region, observing the usual aseptic precautions.

Presentation:
Cardboard boxes containing 5 vials of one dose each freeze-dried vaccine and 5 vials of 1 ml sterile diluent.

Registration holder 
Intervet S.A. (Pty) Ltd
Co. Reg. No. 1991/006580/07