Indications:
For the active immunisation of healthy dogs against Rabies. Nobivac® Rabies may be used to reconstitute the freeze-dried canine vaccines and may be administered in combination with Nobivac® D.

Vaccination leads to a high peak level within 3 weeks, followed by a more or less constant level sufficiently high to provide protection.

Storage Instructions:

• Store in the dark between 2 °C and 8 °C.
• Allow the vaccine to reach room temperature (20 °C and 25 °C) before use.
• Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
• Protect from direct sunlight.

Composition:
The vaccine is an inactivated culture of Rabies virus, cloned out
of strain Pasteur RIV with a potency of > 2,0 i.u. The virus is grown on the BHK-21 Clone CT cell line and inactivated with beta-propiolactone. It is presented as an aqueous aluminium phosphate suspension.

Contents:
Each vial of 10 doses of 1 ml contains Inactivated Rabies Antigen
suspension with a potency per dose of > 2.0 i.u. (Ph.Eur. method) with 0,3 % Aluminium phosphate as adjuvant, Glycine as a buffer and 0,1 mg per dose of Thiomersal as a preservative.

Warnings:

• Do not freeze.
• Avoid intravenous injection.
• After subcutaneous administration occasionally a transient palpable nodule may occur at the site of injection.
• Accidental self injection may lead to a severe allergic reaction. Consult a physician.
• Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
• Keep out of reach of children and uninformed persons.
• Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Precautions:

• Vaccinate healthy animals only.
• Observe aseptic precautions. Ensure that the vaccination equipment (needles, syringes, etc) are clean and sterile prior to use.
• Destroy any unused vaccine, by for example, burning and dispose of all the vaccine containers after vaccination.
• It is good vaccination practice when handling the vaccine to avoid contact with the eyes, hands and clothing.

Directions for Use:

• Use only as directed.
• Shake well before use.
• 1 ml is administered by subcutaneous injection.

VaccinationScheme - Dogs:
 
* Primary vaccination at an age of more than - 3 months
** Re-vaccination every -  3 years

Vaccination leads to a high peak level within 3 weeks followed by a more or less constant level sufficiently high to provide protection.

* Primary vaccination may be administered at an earlier age, but then a repeat vaccination must be given at the age of 3 months.

** Recommended re-vaccination interval is based upon results from challenge experiments. Local regulations in force may require earlier re-vaccinations.

Do not store partially used containers for future use.
Use the entire contents of multi-dose vials when first opened.

Presentation:
Cardboard boxes containing 5 vials of 10 doses each.

Registration holder 
Intervet S.A. (Pty) Ltd
Co. Reg. No. 1991/006580/07