Composition:
Each ml contains 50 mg furosemide.
Preservative: Myristyl picolinium chloride 0,027% m/v.

Pharmacological Classificaiton:
C 19.1 Diuretics.

Pharmacological Action: Furosemide has a diuretic action.

• In cattle, the diuretic effect peaks 3 hours after intramuscular injection and diuresis lasts for about 6 hours.
• In dogs, diuresis starts within 30 minutes to 2 hours, depending on the route of administration.

The diuretic effect and its intensity can be influenced and controlled through the route of administration and the dosage. The rapid onset of effect and its relatively short duration, permit accurate prediction and adjustment of diuresis. This is a great advantage, particularly in the treatment of small animals. Diuresis lasts about 3 hours after intravenous injection.

Indications:
Supportive therapy in all cases in which enhanced diuresis/saluresis can hasten reabsorption of non-inflammatory fluid accumulations of cardiac, renal or other origin from tissues, body cavities, joints, tendon sheaths, etc.

This applies in particular to: non-physical acute oedema of udders before and after parturition, pulmonary and bronchial oedema in diseases of the respiratory tract, hydropericardium, hydrothorax, ascites (also in cirrhosis of the liver), preputial and scrotal oedema, oedema of limbs and wounds after injuries or operations, cerebral oedema and oedema of parasitic origin.

Contra-indications:
Severe liver lesions, renal failure with anuria and acute glomerular nephritis. Hypersensitivity.

Warnings:

Withdrawal period:
Milk for human consumption: 1 day
Meat: 1 day

Therapeutic Scheme:

• Cattle: Treat at intervals of 12 – 24 hours, according to indications and clinical response.
• Horse/Dog/Cat: Treat at intervals of 6 – 8 hours, according to indications and clinical response.
  
  Note: The therapeutic effect may be impaired by increased intake of drinking water. So far as the patient’s condition permits, the amount of drinking water available should be substantially reduced during treatment.

Side-effects and special precautions for use per species:
No side effects.

Known symptoms of overdosage and particulars of its treatment per species:
Symptomatic treatment.

Identification:
Amber glass vials with clear, colourless liquid.

Storage Instructions:
Protect from light and store below 25°C. If stored below 18°C for prolonged periods, the formation of crystals may occur. These physical changes have no adverse effect on the efficacy/safety of the product and are reversible, if stored for 24 hours above 20°C.

Presentation:
10 ml vials individually packed.

Registration holder: 
Intervet S.A. (Pty) Ltd
Co. Reg. No. 1991/006580/07